Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974443 | 0.95 | HRH3 (0.46) | HRH3HRH4NAAA | |
| SCHEMBL7971425 | 0.94 | HRH3 (0.50) | HRH3HRH4NAAA | |
| SCHEMBL7994817 | 0.79 | ACHE (0.47) | HRH3HRH4 | |
| SCHEMBL7977480 | 0.79 | EPHX1 (0.51) | HRH3HRH4NAAA | |
| SCHEMBL8798811 | 0.78 | HRH3 (0.39) | HRH3HRH4 | |
| SCHEMBL7987133 | 0.78 | HRH3 (0.46) | HRH3HRH4 | |
| SCHEMBL5157531 | 0.77 | NAAA (0.35) | HRH3HRH4NAAA | |
| SCHEMBL4383626 | 0.77 | ACHE (0.53) | HRH3 | |
| SCHEMBL4384378 | 0.76 | ACHE (0.52) | — | |
| SCHEMBL7974350 | 0.76 | NPC1 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | disclosed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5559113-A | ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | 1996-09-24 | — | — | US | disclosed |