Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971425 | 0.83 | HRH3 (0.50) | EPHX1HRH3HRH4NAAA | |
| SCHEMBL7974443 | 0.79 | HRH3 (0.46) | HRH3HRH4NAAA | |
| SCHEMBL7977157 | 0.79 | HRH3 (0.47) | HRH3HRH4NAAA | |
| SCHEMBL12196113 | 0.77 | EPHX1 (0.58) | EPHX1ALDH1A1 | |
| SCHEMBL4376605 | 0.76 | HRH3 (0.46) | HRH3HRH4 | |
| SCHEMBL5157531 | 0.76 | NAAA (0.35) | HRH3HRH4NAAA | |
| SCHEMBL7987244 | 0.75 | SMN1; SMN2 (0.43) | HRH3NAAA | |
| SCHEMBL4384276 | 0.75 | SMN1; SMN2 (0.43) | HRH3NAAA | |
| SCHEMBL13625188 | 0.74 | EPHX1 (0.78) | EPHX1NAAAALDH1A1 | |
| SCHEMBL4381424 | 0.74 | ALDH1A1 (0.36) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | disclosed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5559113-A | ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | 1996-09-24 | — | — | US | disclosed |