SCHEMBL7977172

SCHEMBL7977172

NC(=O)CCC(=O)c1ccncc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C19 P33261 2/20 0.52
PLOD2 O00469 2/20 0.52
PLOD3 O60568 2/20 0.52
PLOD1 Q02809 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
HIF1A Q16665 1/20 0.52
CTNNB1 P35222 2/20 0.50
WNT3A P56704 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MPO P05164 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CYP2A6 P11509 1/20 0.50
NAPRT Q6XQN6 1/20 0.46
MMP1 P03956 1/20 0.46
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988710 0.89 CYP2C19 (0.61) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL16404441 0.81 CYP1A2 (0.59) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL10843960 0.81 NR4A2 (0.65) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL9195700 0.81 ALDH1A1 (0.77) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL5163555 0.81 CYP3A4 (0.64) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL7977170 0.79 CTNNB1 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL31561725 0.78 ALDH1A1 (0.59) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL660788 0.78 NR4A2 (0.68) CYP1A2CYP3A4CYP2C19ALDH1A1HPGD
SCHEMBL23891579 0.77 CYP3A4 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2
SCHEMBL23891607 0.77 CYP3A4 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19PLOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed