Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | WNT3A | P56704 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL11597195 | 0.90 | NR4A2 (0.57) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL1478436 | 0.89 | TDP1 (0.72) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL6156726 | 0.89 | TDP1 (0.79) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL30121738 | 0.88 | NR4A2 (0.85) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL719034 | 0.88 | NR4A2 (0.85) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL11798285 | 0.88 | SMN1; SMN2 (0.72) | NR4A2MAPTL3MBTL1LMNAALDH1A1 | |
| SCHEMBL1479260 | 0.87 | L3MBTL1 (0.83) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL10789857 | 0.84 | TSHR (0.52) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL7043064 | 0.83 | NR4A2 (0.63) | NR4A2MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL1808054 | 0.81 | TDP1 (0.67) | NR4A2MAPTTDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121433-B | Antiviral compound, its pharmaceutically acceptable salt or optical isomer, the method for preparing them and the pharmaceutical composition for being used to prevent or treat viral disease for containing the same as active ingredient | 韩国化学研究院 | 2018-01-23 | — | — | CN | claimed |
| CN-103059215-A | Glycine betaine ester intelligent hydrogel relatively controllable in structure and preparation method and application | UNIV SOUTH CHINA TECH | 2013-04-24 | — | — | CN | claimed |
| WO-1999067196-A1 | FLUOXETINE PROCESS FROM BENZOYLPROPIONIC ACID | SEPRACOR INC. (US) | 1999-12-29 | — | — | WO | claimed |
| EP-3507275-B1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-10703754-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | ELI LILLY AND COMPANY (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELI LILLY AND COMPANY | 2019-06-27 | — | — | US | disclosed |
| US-20180265511-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELI LILLY AND COMPANY | 2018-09-20 | — | — | US | disclosed |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2018-07-19 | — | — | US | disclosed |
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2018-05-17 | — | — | US | disclosed |
| CN-106565621-A | Isoxaflutole synthesizing method | 上虞颖泰精细化工有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-105837657-A | Chemical total synthesis method of polypeptide without amino acid | 陈铭 | 2016-08-10 | — | — | CN | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-3936468-A | PSYCHOTROPIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-03 | — | — | US | disclosed |
| US-3936468-A | PSYCHOTROPIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703754-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | ELANE, CASP3, MMP8 | NR4A2 2731/4885MAPT 2844/4885TDP1 1726/4885 |
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | NR4A2 1643/4885MAPT 568/4885TDP1 2578/4885 |
| US-20180265511-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | NR4A2 2731/4885MAPT 2844/4885TDP1 1726/4885 |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | NCS1, DAXX, CNDP2 | NR4A2 1034/4885MAPT 3655/4885TDP1 617/4885 |
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | NR4A2 2731/4885MAPT 2844/4885TDP1 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.