SCHEMBL7977261

SCHEMBL7977261

[c]1ccc2c(c1)c1ccccc1n2Cc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.72
P2RX4 Q99571 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HDAC6 Q9UBN7 2/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC10 Q969S8 1/20 0.45
PGR P06401 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056944 0.90 CYP19A1 (0.72) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
SCHEMBL30007452 0.85 CYP19A1 (1.00) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
SCHEMBL151053 0.85 CYP19A1 (1.00) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
Bromide SCHEMBL28888744 0.83 CYP19A1 (0.95) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
SCHEMBL9398256 0.83 CYP19A1 (0.95) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
Ammonia Solution, Strong SCHEMBL29210102 0.83 CYP19A1 (0.95) CYP19A1P2RX4SMN1; SMN2MEN1KMT2A
SCHEMBL334753 0.81 ALDH1A1 (0.55) CYP19A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL13957035 0.79 CYP19A1 (0.86) CYP19A1P2RX4CYP1A2CYP2C19HDAC6
SCHEMBL9145870 0.79 KDM4E (0.72) MEN1KMT2AKDM4EMAPK1ALDH1A1
SCHEMBL16100095 0.78 CYP19A1 (0.42) CYP19A1P2RX4MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4355823-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1982-10-26 US claimed
CN-115696945-A Light emitting device 株式会社半导体能源研究所 2023-02-03 CN disclosed
CN-110382502-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2022-11-29 CN disclosed
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed
US-4966983-A PRESSURE OR HEAT SENSITIVE ELEMENTS BASF AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
US-4841050-A Carbazole containing benzopyrans BASF AKTIENGESELLSCHAFT (DE) 1989-06-20 US disclosed
EP-0236973-A2 Benzopyranes and their use in a recording system BASF Aktiengesellschaft (DE) 1987-09-16 EP disclosed
US-4369326-A CHROMOGENS FOR PRESSURE SENSITIVE OR HEAT SENSITIVE RECORDING MATERIAL CIBA-GEIGY CORPORATION (US) 1983-01-18 US disclosed
US-4355823-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1982-10-26 US disclosed
US-4275005-A DYES FOR HEAT OR PRESSURE SENSITIVE DUPLICATION CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed
US-4254032-A COLOR FORMERS FOR HEAT SENSITIVE OR PRESSURE SENSITIVE ELEMENTS CIBA-GEIGY CORPORATION (US) 1981-03-03 US disclosed