Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 14/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977321 | 0.88 | NPY5R (1.00) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL6826919 | 0.82 | NPY5R (0.76) | NPY5RSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL20236734 | 0.76 | SMN1; SMN2 (1.00) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL20237020 | 0.74 | SMN1; SMN2 (0.68) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7963464 | 0.72 | NPY5R (1.00) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL12477049 | 0.72 | SMN1; SMN2 (0.64) | NPY5RSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL7963462 | 0.71 | NPY5R (1.00) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL178526 | 0.71 | NPC1 (0.71) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL104586 | 0.70 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5372624 | 0.70 | SMN1; SMN2 (0.60) | NPY5RSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |