Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 14/20 | 0.45 |
| ▸ | SCN1A | P35498 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815765 | 0.84 | LMNA (0.53) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL6814761 | 0.83 | SCN8A (0.51) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL6815754 | 0.81 | SCN8A (0.49) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL6816056 | 0.79 | SCN8A (0.47) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL6815674 | 0.78 | SMN1; SMN2 (0.47) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL6814665 | 0.77 | SCN8A (0.51) | LMNAMAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL7914993 | 0.76 | ALDH1A1 (0.40) | LMNAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6815096 | 0.72 | SCN8A (0.56) | SCN8ASCN1A | |
| SCHEMBL6814767 | 0.71 | SCN8A (0.48) | LMNATP53SCN8ASCN1A | |
| SCHEMBL7638965 | 0.71 | ALDH1A1 (0.52) | LMNAMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |