Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RORC | P51449 | 7/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899363 | 0.90 | ALDH1A1 (0.63) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL15899281 | 0.87 | ALDH1A1 (0.62) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL15899227 | 0.86 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13958870 | 0.81 | KMT2A (0.67) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7726129 | 0.81 | NPY5R (0.61) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9764909 | 0.81 | KMT2A (0.63) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7974078 | 0.81 | MAPT (1.00) | MAPTLMNAALDH1A1KMT2ANPY5R | |
| SCHEMBL20181195 | 0.79 | KMT2A (0.61) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30148028 | 0.79 | KMT2A (0.61) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30523185 | 0.79 | KMT2A (0.61) | MAPTLMNAALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |