Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165943 | 0.75 | ELANE (0.61) | TP53SMN1; SMN2LTA4HNPC1MAPT | |
| SCHEMBL16726530 | 0.72 | LOXL2 (0.53) | TDP1ALDH1A1TP53SMN1; SMN2LTA4H | |
| SCHEMBL13481254 | 0.72 | NPC1 (0.50) | TDP1ALDH1A1TP53SMN1; SMN2LTA4H | |
| SCHEMBL9499089 | 0.72 | NPC1 (0.52) | ALDH1A1TP53SMN1; SMN2LTA4HKCNH2 | |
| SCHEMBL30711536 | 0.71 | PSMB8 (0.50) | TDP1ALDH1A1TP53SMN1; SMN2LTA4H | |
| SCHEMBL18013091 | 0.71 | ELANE (0.64) | ALDH1A1TP53SMN1; SMN2LTA4HKCNH2 | |
| SCHEMBL18013086 | 0.71 | MAPT (0.53) | TDP1ALDH1A1TP53LTA4HKCNH2 | |
| SCHEMBL9803899 | 0.71 | LTA4H (0.46) | TDP1ALDH1A1TP53SMN1; SMN2LTA4H | |
| SCHEMBL10924385 | 0.71 | NPC1 (0.44) | TDP1ALDH1A1TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL10509180 | 0.70 | TDP1 (0.50) | TDP1ALDH1A1GLATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017993-A1 | ALKYLPIPERIDI NYLBENZO [D] ISOXAZOLE DERIVATIVES HAVING PSYCHOTROPIC ACTIVITY, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS Gyógyszergyár Rt. (HU) | 2001-03-15 | — | — | WO | disclosed |