Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117280 | 0.91 | PNP (0.45) | PNPALDH1A1HIF1APOLBMEN1 | |
| SCHEMBL7111860 | 0.91 | PNP (0.45) | PNPALDH1A1HIF1APOLBMEN1 | |
| SCHEMBL7117422 | 0.85 | PNP (0.51) | CNOT7PNPALDH1A1HIF1APOLB | |
| SCHEMBL7111074 | 0.84 | PNP (0.44) | PNPBACE1ALDH1A1HIF1AMEN1 | |
| SCHEMBL7120152 | 0.83 | PNP (0.45) | PNPBACE1ALDH1A1HIF1AMEN1 | |
| SCHEMBL7113168 | 0.80 | PNP (0.43) | PNPALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7113849 | 0.80 | PNP (0.43) | PNPALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7977484 | 0.80 | PNP (0.41) | PNPBACE1BRD4 | |
| SCHEMBL7110374 | 0.80 | SMN1; SMN2 (0.48) | PNPKMT2ASMN1; SMN2 | |
| SCHEMBL7112398 | 0.79 | ALDH1A1 (0.47) | PNPBACE1TRPA1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | claimed |