Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 4/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117280 | 0.81 | PNP (0.45) | PNPBRD4 | |
| SCHEMBL7111860 | 0.81 | PNP (0.45) | PNPBRD4 | |
| SCHEMBL7977483 | 0.80 | CNOT7 (0.46) | PNPBRD4BACE1 | |
| SCHEMBL7117422 | 0.77 | PNP (0.51) | PNPBRD4 | |
| SCHEMBL7112398 | 0.75 | ALDH1A1 (0.47) | PNPTLR7BACE1 | |
| SCHEMBL7111074 | 0.73 | PNP (0.44) | PNPBRD4BACE1 | |
| SCHEMBL7120152 | 0.73 | PNP (0.45) | PNPBRD4BACE1 | |
| SCHEMBL7113849 | 0.70 | PNP (0.43) | PNP | |
| SCHEMBL7113168 | 0.70 | PNP (0.43) | PNP | |
| SCHEMBL7110374 | 0.70 | SMN1; SMN2 (0.48) | PNPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | claimed |