Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989922 | 0.87 | SIRT2 (0.48) | SIRT2SIRT1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7989978 | 0.85 | SIRT2 (0.61) | SIRT2SIRT1KDM4EALDH1A1MTOR | |
| SCHEMBL7977895 | 0.85 | SIRT2 (0.61) | SIRT2SIRT1KDM4EALDH1A1MTOR | |
| SCHEMBL7992000 | 0.80 | MAPT (0.50) | SIRT2SIRT1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7988996 | 0.79 | RAB9A (0.44) | SIRT2SIRT1KDM4EALDH1A1MTOR | |
| SCHEMBL7988152 | 0.79 | SIRT2 (0.61) | SIRT2SIRT1KDM4EALDH1A1LMNA | |
| SCHEMBL7992080 | 0.77 | MAPT (0.41) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7991536 | 0.77 | SIRT2 (0.52) | SIRT2SIRT1KDM4EALDH1A1MTOR | |
| SCHEMBL7989361 | 0.77 | SIRT2 (0.52) | SIRT2SIRT1KDM4EALDH1A1MTOR | |
| SCHEMBL7987913 | 0.77 | SIRT2 (0.59) | SIRT2SIRT1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |