Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987913 | 0.92 | SIRT2 (0.59) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7989361 | 0.91 | SIRT2 (0.52) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7978031 | 0.91 | SIRT2 (0.61) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7977895 | 0.90 | SIRT2 (0.61) | SIRT2SIRT1KDM4ELMNAMAPT | |
| SCHEMBL7977684 | 0.85 | SIRT2 (0.60) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7991747 | 0.84 | PARP1 (0.53) | SIRT2SIRT1KDM4EMAPTALOX5 | |
| SCHEMBL7988152 | 0.83 | SIRT2 (0.61) | SIRT2SIRT1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7991536 | 0.82 | SIRT2 (0.52) | SIRT2SIRT1KDM4ELMNAMAPT | |
| SCHEMBL7991809 | 0.82 | SIRT2 (0.59) | SIRT2SIRT1KDM4EMAPTALOX5 | |
| SCHEMBL7989867 | 0.81 | SIRT2 (0.58) | SIRT2SIRT1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |