Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977684 | 0.87 | SIRT2 (0.60) | SIRT2SIRT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7988996 | 0.81 | RAB9A (0.44) | SIRT2SIRT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7991747 | 0.81 | PARP1 (0.53) | SIRT2SIRT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7991773 | 0.81 | PARP1 (0.51) | SIRT2SIRT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7988114 | 0.77 | PIN1 (0.48) | MAPK1PARP1PIN1CHEK2HDAC4 | |
| SCHEMBL7989265 | 0.76 | SIRT2 (0.47) | SIRT2SIRT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7977456 | 0.73 | DHODH (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7989851 | 0.72 | PARP1 (0.45) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7991959 | 0.72 | SMN1; SMN2 (0.44) | SIRT2SIRT1ALDH1A1KMT2AMAPT | |
| SCHEMBL7977819 | 0.71 | CHEK2 (0.51) | SIRT2SIRT1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |