Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399484 | 1.00 | — | — | |
| SCHEMBL3632230 | 1.00 | CYP3A4 (0.39) | CYP3A4TSHRCA2EPHX2ALDH1A1 | |
| SCHEMBL4400003 | 0.92 | CYP3A4 (0.38) | CYP3A4TSHRCA2EPHX2ALDH1A1 | |
| SCHEMBL11140966 | 0.92 | CYP3A4 (0.38) | CYP3A4TSHRCA2EPHX2ALDH1A1 | |
| SCHEMBL4264825 | 0.89 | ALDH1A1 (0.36) | CYP3A4TSHRCA2ALDH1A1 | |
| SCHEMBL5176470 | 0.89 | ALDH1A1 (0.36) | CYP3A4TSHRCA2ALDH1A1 | |
| SCHEMBL4400491 | 0.89 | ALDH1A1 (0.41) | CYP3A4TSHRCA2ALDH1A1MEN1 | |
| SCHEMBL5173665 | 0.83 | ALDH1A1 (0.41) | CYP3A4TSHRCA2ALDH1A1MEN1 | |
| SCHEMBL4392852 | 0.83 | ALDH1A1 (0.41) | CYP3A4TSHRCA2ALDH1A1MEN1 | |
| SCHEMBL2397059 | 0.82 | CA2 (0.41) | CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |