Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12073562 | 0.81 | ADRB1 (0.46) | ALDH1A1 | |
| SCHEMBL249009 | 0.80 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4940197 | 0.80 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21541880 | 0.80 | SLC6A2 (0.46) | — | |
| SCHEMBL22837879 | 0.80 | HRH3 (0.40) | — | |
| SCHEMBL14048133 | 0.80 | MAPT (0.45) | ALDH1A1KDM4E | |
| SCHEMBL3567979 | 0.80 | MAPT (0.49) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28307860 | 0.80 | LSS (0.48) | KDM4E | |
| SCHEMBL22837878 | 0.79 | MBTD1 (0.47) | SMN1; SMN2 | |
| SCHEMBL19251500 | 0.78 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |