Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.56 |
| ▸ | F10 | P00742 | 11/20 | 0.56 |
| ▸ | PLG | P00747 | 7/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | ITK | Q08881 | 5/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967842 | 0.87 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7984703 | 0.84 | F2 (0.64) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL4451660 | 0.82 | F2 (0.58) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7415365 | 0.82 | F2 (0.58) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7968917 | 0.77 | F2 (0.48) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7984977 | 0.75 | F2 (0.75) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7984275 | 0.74 | F2 (0.70) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7980030 | 0.72 | F2 (1.00) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7101562 | 0.71 | F2 (0.52) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7968268 | 0.71 | F2 (0.45) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |