Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.46 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030095 | 0.87 | GRIN1 (0.63) | ATICGRIN1GRIN2BF2BRD4 | |
| Hydrochloric Acid SCHEMBL7978468 | 0.82 | F2 (0.78) | ATICGRIN1GRIN2BF2BRD4 | |
| SCHEMBL7978349 | 0.78 | KMT2A (0.74) | GRIN1GRIN2BPARP1KMT2AMEN1 | |
| SCHEMBL7967816 | 0.77 | DHFR (0.49) | ATICGRIN1GRIN2BPARP1KMT2A | |
| SCHEMBL8026131 | 0.77 | GRIN1 (0.52) | ATICGRIN1GRIN2BF2BRD4 | |
| SCHEMBL8028956 | 0.76 | PTPN1 (0.60) | KMT2AARMEN1ALDH1A1LMNA | |
| SCHEMBL8027058 | 0.74 | F2 (0.70) | F2BRD4BRPF1BRD1ALDH1A1 | |
| SCHEMBL8029978 | 0.74 | F2 (0.60) | F2BRD4BRPF1BRD1LMNA | |
| SCHEMBL7428683 | 0.74 | BRPF1 (0.52) | ATICBRD4BRPF1BRD1AR | |
| SCHEMBL7981348 | 0.74 | BRPF1 (0.56) | F2BRD4BRPF1BRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |