Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964390 | 0.88 | TERT (0.33) | TERT | |
| SCHEMBL7977886 | 0.87 | SLC5A1 (0.36) | TERTHTR1ADRD2DRD3 | |
| SCHEMBL7978010 | 0.84 | DRD2 (0.32) | TERTDRD2DRD3 | |
| SCHEMBL7977920 | 0.80 | NR3C2 (0.45) | — | |
| SCHEMBL12188290 | 0.73 | HTR1A (0.37) | PDE3BPDE3ACYP11B1CYP11B2HTR1A | |
| SCHEMBL7980627 | 0.72 | — | — | |
| SCHEMBL7965406 | 0.71 | — | — | |
| SCHEMBL12981165 | 0.68 | PIK3CG (0.36) | — | |
| SCHEMBL7975782 | 0.68 | SLC5A1 (0.37) | DRD2DRD3 | |
| SCHEMBL17813516 | 0.67 | HTR1D (0.41) | TERTPDE3BPDE3AGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |