Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830035 | 0.79 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL29359720 | 0.79 | SMN1; SMN2 (0.44) | CRBNGAAMAPK1PTK2CHEK1 | |
| SCHEMBL14446905 | 0.76 | SMN1; SMN2 (0.54) | CRBNGAAMAPK1PTK2CHEK1 | |
| SCHEMBL22144519 | 0.73 | CRBN (0.49) | CRBNDDB1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL7833769 | 0.73 | SMN1; SMN2 (0.51) | GAAMAPK1METSMN1; SMN2ALDH1A1 | |
| SCHEMBL565271 | 0.73 | SMN1; SMN2 (0.53) | CRBNGAAMAPK1PTK2CHEK1 | |
| SCHEMBL30052176 | 0.72 | EP300 (0.50) | CRBNGAAMAPK1PTK2CHEK1 | |
| SCHEMBL1885114 | 0.72 | EP300 (0.50) | CRBNGAAMAPK1PTK2CHEK1 | |
| SCHEMBL1530734 | 0.71 | CRBN (1.00) | CRBNDDB1GAAGSK3AGSK3B | |
| SCHEMBL30218779 | 0.70 | SMN1; SMN2 (0.47) | CRBNGAAMAPK1PTK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051320-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| US-11932635-B2 | CRBN ligands and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-11512080-B2 | CRBN ligands and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-11-29 | — | — | US | disclosed |
| EP-4003981-A1 | SUBSTITUTED N-PHENYL URACILS, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-06-01 | — | — | EP | disclosed |
| EP-3737675-A1 | CRBN LIGANDS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2020-11-05 | — | — | US | disclosed |
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2020-11-05 | — | — | US | disclosed |
| US-9783509-B2 | Six-membered C-N-linked aryl sulfide derivatives and aryl sulfoxide derivatives as pest conrol agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-10-10 | — | — | US | disclosed |
| US-20160251321-A1 | SIX-MEMBERED C-N-LINKED ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE ERIVATVES AS PEST CONROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-09-01 | — | — | US | disclosed |
| EP-3019481-A1 | SIX-MEMBERED C-N-LINKED ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-05-18 | — | — | EP | disclosed |
| CN-105517995-A | Six-membered C-N bonded aryl sulfide and aryl sulfoxide derivatives as pesticides | BAYER CROPSCIENCE AG | 2016-04-20 | — | — | CN | disclosed |
| WO-2015004028-A1 | SIX-MEMBERED C-N-LINKED ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-01-15 | — | — | WO | disclosed |
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |
| WO-1997010220-A1 | URACIL DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | CRBN 1/4885DDB1 304/4885GAA 3110/4885 |
| US-11932635-B2 | CRBN ligands and uses thereof | CRBN, CRKL, ERBB3 | CRBN 1/4885DDB1 304/4885GAA 3110/4885 |
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | CRBN 1/4885DDB1 304/4885GAA 3110/4885 |
| US-20250051320-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | CRBN 1/4885DDB1 304/4885GAA 3110/4885 |
| US-20160251321-A1 | SIX-MEMBERED C-N-LINKED ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE ERIVATVES AS PEST CONROL AGENTS | CBR3, ERLIN1, CYCS | CRBN 30/4885DDB1 4510/4885GAA 1361/4885 |
| US-11512080-B2 | CRBN ligands and uses thereof | CRBN, CRKL, ERBB3 | CRBN 1/4885DDB1 304/4885GAA 3110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.