Uracil

Uracil

SCHEMBL7977993

O=c1cc[nH]c(=O)[nH]1.c1ccncc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.68
MMP2 P08253 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOTUM Q6P988 2/20 0.34
MAPT P10636 2/20 0.33
BTK Q06187 2/20 0.33
GSK3B P49841 1/20 0.33
ALDH1A1 P00352 3/20 0.32
PDE3B Q13370 3/20 0.32
PDE3A Q14432 3/20 0.32
FKBP5 Q13451 1/20 0.32
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL27698159 0.98 CRBN (0.65) CRBNMMP2TP53TSHRNAPRT
Uracil SCHEMBL28278941 0.93 CRBN (0.59) CRBNMMP2TP53TSHRNAPRT
Uracil SCHEMBL27721297 0.90 CRBN (0.55) CRBNMMP2TP53TDP1NOTUM
Uracil SCHEMBL467925 0.88 CRBN (0.68) CRBNMMP2TP53NOTUMMAPT
Uracil SCHEMBL27799965 0.87 CRBN (0.90) CRBNMMP2TP53NOTUMMAPT
Uracil SCHEMBL8235 0.82
Uracil SCHEMBL3798527 0.82 CRBN (1.00) CRBNMMP2TP53TSHRNOTUM
Uracil SCHEMBL5089507 0.82
Uracil SCHEMBL11607890 0.82
Uracil SCHEMBL18132339 0.80 CRBN (0.57) CRBNMMP2TP53PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175005-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2023-06-08 US claimed
CN-114249710-A Herbicidal uracils 巴斯夫欧洲公司 2022-03-29 CN claimed
US-11247980-B2 Herbicidal uracilpyrid BASF SE (DE) 2022-02-15 US claimed
EP-3464261-B1 HERBICIDAL URACILPYRID BASF SE (DE) 2021-07-07 EP claimed
WO-2021018664-A1 HERBICIDAL URACILPYRIDINES BASF SE (DE) 2021-02-04 WO claimed
US-20210002662-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2021-01-07 US claimed
US-20200317634-A1 HERBICIDAL URACILPYRID BASF SE (DE) 2020-10-08 US claimed
EP-3716765-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2020-10-07 EP claimed
EP-4370505-A1 HERBICIDAL PHENYLURACILS BASF SE (DE) 2024-05-22 EP disclosed
US-11879132-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2024-01-23 US disclosed
US-20230175005-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2023-06-08 US disclosed
CN-115707690-A 3-isoxazolidinone compound, preparation method thereof, weeding composition and application 青岛清原化合物有限公司 2023-02-21 CN disclosed
WO-2023285222-A1 HERBICIDAL PHENYLURACILS BASF SE (DE) 2023-01-19 WO disclosed
CN-115354039-A Method for creating new gene in organism and application 青岛清原化合物有限公司 2022-11-18 CN disclosed
WO-2018114759-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF Agro B.V. (NL) 2018-06-28 WO disclosed
WO-2017202768-A1 HERBICIDAL URACILPYRID BASF SE (DE) 2017-11-30 WO disclosed
WO-2017202768-A1 HERBICIDAL URACILPYRID BASF SE (DE) 2017-11-30 WO disclosed
CN-102083845-B Cyclopropyl polymerase inhibitors 森托科尔奥索生物科技产品股份有限公司 2016-09-14 CN disclosed
CN-101234337-A Silica matrix chromatogram packing UNIV TIANJIN (CN) 2008-08-06 CN disclosed
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175005-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX CRBN 2328/4885MMP2 2396/4885TP53 883/4885
US-11879132-B2 Plants having increased tolerance to herbicides PAOX, PNKP, PPOX CRBN 2229/4885MMP2 4353/4885TP53 472/4885
US-20200317634-A1 HERBICIDAL URACILPYRID UNG, UMPS, DPYD CRBN 4606/4885MMP2 2032/4885TP53 1133/4885
US-11247980-B2 Herbicidal uracilpyrid UNG, UMPS, DPYD CRBN 4606/4885MMP2 2032/4885TP53 1133/4885
US-20210002662-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX CRBN 2328/4885MMP2 2396/4885TP53 883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.