SCHEMBL7978002

SCHEMBL7978002

CS(=O)(=O)n1c(C(F)(F)F)cc(=O)n(-c2ccc3c(n2)NC(=O)CO3)c1=O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 13/20 0.42
NR3C1 P04150 2/20 0.39
PGR P06401 1/20 0.34
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977920 0.86 NR3C2 (0.45) NR3C2NR3C1PGRKCNH2
SCHEMBL7964385 0.84 NR3C2 (0.43) NR3C2NR3C1
SCHEMBL7975801 0.83 NR3C2 (0.43) NR3C2NR3C1PGR
SCHEMBL7964421 0.77 NR3C2 (0.40) NR3C2NR3C1KCNH2
SCHEMBL7974838 0.75 NR3C2 (0.44) NR3C2NR3C1
SCHEMBL7977805 0.73 NR3C2 (0.43) NR3C2NR3C1
SCHEMBL7977926 0.66 TERT (0.35)
SCHEMBL7977855 0.65 NR3C2 (0.49) NR3C2NR3C1
SCHEMBL18950883 0.63 NR3C2 (0.61) NR3C2NR3C1
SCHEMBL7964390 0.63 TERT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed