Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171315 | 0.80 | KIF11 (0.50) | KIF11KCNH2TAAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL11784733 | 0.80 | KIF11 (0.46) | KIF11KCNH2LMNATAAR1SMN1; SMN2 | |
| SCHEMBL12637139 | 0.76 | KIF11 (0.53) | KIF11KCNH2TAAR1KCNN4 | |
| SCHEMBL2065992 | 0.75 | TAAR1 (0.52) | KIF11KCNH2LMNATAAR1SMN1; SMN2 | |
| SCHEMBL10805592 | 0.73 | KIF11 (0.50) | KIF11LMNATAAR1KCNN4 | |
| SCHEMBL17537036 | 0.71 | KIF11 (0.57) | KIF11LMNATAAR1KCNN4 | |
| SCHEMBL20357549 | 0.70 | KIF11 (0.56) | KIF11KCNH2TAAR1SMN1; SMN2KCNN4 | |
| SCHEMBL8352929 | 0.70 | KIF11 (0.43) | KIF11TAAR1 | |
| SCHEMBL6470484 | 0.69 | LMNA (0.50) | LMNATAAR1KCNN4 | |
| SCHEMBL11808675 | 0.68 | KIF11 (0.46) | KIF11KCNH2TAAR1SMN1; SMN2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |