SCHEMBL7978091

SCHEMBL7978091

CNc1nc(NC(C)CCc2ccccc2)nc(C(F)(F)F)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.44
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
G6PD P11413 1/20 0.41
TLR7 Q9NYK1 1/20 0.41
EPHX2 P34913 1/20 0.40
KCNH3 Q9ULD8 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.40
APP P05067 1/20 0.39
BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960038 0.87 SCN9A (0.41) SCN9AG6PDTLR7ALDH1A1
SCHEMBL8101266 0.78 HTR7 (0.46) SCN9AG6PDKCNH3ALDH1A1CYP1A2
SCHEMBL7978040 0.78 HTR7 (0.46) SCN9AG6PDKCNH3ALDH1A1CYP1A2
SCHEMBL7978055 0.77 NPR3 (0.44) SCN9AEPHX2KCNH3ALDH1A1MEN1
SCHEMBL6246350 0.76 HTR7 (0.44) SCN9AG6PDALDH1A1CYP1A2CYP2C9
SCHEMBL7964656 0.76 ALDH1A1 (0.46) SCN9AG6PDALDH1A1CYP1A2CYP2C9
SCHEMBL7954573 0.75 KCNH2 (0.41) ALDH1A1MEN1KMT2A
SCHEMBL8097539 0.75 ADORA3 (0.43) SCN9AEPHX2MEN1HTTKMT2A
SCHEMBL8097547 0.75 SIRT5 (0.43) SCN9AEPHX2KCNH3ALDH1A1MEN1
SCHEMBL8085109 0.74 HTR7 (0.46) SCN9AG6PDALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271178-B1 APPLYING TO PLANTS; CONTROLLING WEEDS BAYER AG (DE) 2001-08-07 US disclosed
EP-0932605-A1 SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AG (DE) 1999-08-04 EP disclosed
WO-1998015538-A1 SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed