Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.84 | GAA (0.43) | GAAACLYMAPTPOLBTP53 | |
| SCHEMBL6790398 | 0.81 | GAA (0.50) | GAAACLYMAPTTP53KDR | |
| SCHEMBL7993931 | 0.78 | GAA (0.41) | GAAMAPTPOLBTP53KDR | |
| SCHEMBL8001808 | 0.77 | GAA (0.42) | GAAMAPTTP53KDRP2RY14 | |
| SCHEMBL7995977 | 0.77 | ACLY (0.39) | GAAACLYMAPTPOLBTP53 | |
| SCHEMBL7983540 | 0.77 | GAA (0.40) | GAAMAPTPOLBTP53KDR | |
| SCHEMBL7994270 | 0.76 | GAA (0.39) | GAAMAPTPOLBTP53KDR | |
| SCHEMBL6245104 | 0.74 | GAA (0.41) | GAAACLYMAPTPOLBTP53 | |
| SCHEMBL7972175 | 0.74 | GAA (0.59) | GAAACLYMAPTPOLBTP53 | |
| SCHEMBL7994435 | 0.73 | GAA (0.37) | GAAMAPTPOLBTP53KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055142-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |