Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552512 | 0.78 | MAPT (0.37) | MAPTSLC6A3SLC6A2SLC6A4TP53 | |
| SCHEMBL25860652 | 0.65 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4TP53 | |
| SCHEMBL19397276 | 0.63 | POLB (0.62) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3058001 | 0.63 | KMT2A (0.35) | — | |
| SCHEMBL14097153 | 0.63 | ALDH1A1 (0.63) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11842181 | 0.62 | ALDH1A1 (0.38) | SLC6A3SLC6A4 | |
| SCHEMBL18956093 | 0.62 | SLC6A4 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL12303028 | 0.62 | ALDH1A1 (0.51) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL31378653 | 0.61 | CYP1A2 (0.34) | SLC6A3SLC6A4 | |
| SCHEMBL621079 | 0.61 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281221-B1 | Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions | HOECHST SCERING AGREVO GMBH (DE) | 2001-08-28 | — | — | US | disclosed |