Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241535 | 1.00 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL32671796 | 0.83 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL12732638 | 0.83 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7978272 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL1094432 | 0.81 | MGLL (0.48) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL29955080 | 0.81 | MGLL (0.48) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL31145649 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7978273 | 0.80 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL23191274 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL10015449 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |