Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241535 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7978271 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7978272 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7774782 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7774803 | 0.73 | TRPA1 (0.48) | ALDH1A1ALOX15HSD17B10MAPTGAA | |
| SCHEMBL12732638 | 0.69 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL32671796 | 0.69 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL50705 | 0.67 | ALDH1A1 (1.00) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL29358687 | 0.67 | ALDH1A1 (1.00) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL12078076 | 0.65 | ALDH1A1 (0.95) | ALDH1A1ALOX15HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |