Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978437 | 1.00 | CYP1A2 (0.46) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7976510 | 0.87 | PDGFRB (0.50) | CYP1A2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16418161 | 0.84 | RAB9A (0.56) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16418160 | 0.84 | RAB9A (0.56) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5208919 | 0.84 | TTR (0.45) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1146111 | 0.84 | RAB9A (0.52) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29785305 | 0.83 | ALDH1A1 (0.43) | HSD17B10ALDH1A1CYP3A4TDP1GAA | |
| SCHEMBL309725 | 0.83 | ALDH1A1 (0.43) | HSD17B10ALDH1A1CYP3A4TDP1GAA | |
| SCHEMBL14915592 | 0.83 | PKM (0.50) | CYP1A2HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4283725 | 0.82 | CYP1A2 (0.53) | CYP1A2RAB9ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055138-A1 | AZOLE DERIVATIVES, THEIR PREPARATION AND USE | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |