Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962474 | 0.82 | ALOX5 (0.55) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL26987673 | 0.82 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL27136379 | 0.82 | ALOX5 (0.62) | ALOX5 | |
| Hydrochloric Acid SCHEMBL7962472 | 0.81 | ALOX5 (0.54) | ALOX5KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL11192241 | 0.78 | ALOX5 (0.60) | ALOX5KDM4EMEN1LMNAKMT2A | |
| SCHEMBL13971424 | 0.77 | SLC7A5 (0.69) | MAPTKDM4EMEN1LMNABLM | |
| SCHEMBL9164980 | 0.77 | SLC7A5 (0.69) | MAPTKDM4EMEN1LMNABLM | |
| SCHEMBL93516 | 0.76 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNABLM | |
| SCHEMBL660499 | 0.76 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNABLM | |
| SCHEMBL29397858 | 0.76 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |