SCHEMBL7962474

SCHEMBL7962474

CCOC(=O)C(N)Cc1cccc2c1oc1ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
KDM4E B2RXH2 5/20 0.47
AHR P35869 1/20 0.47
ADORA3 P0DMS8 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
LMNA P02545 2/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7962472 0.99 ALOX5 (0.54) ALOX5KDM4EAHRADORA3CYP1A2
SCHEMBL7978519 0.82 ALOX5 (0.62) ALOX5KDM4ECYP2C9ALDH1A1HPGD
SCHEMBL7262986 0.80 KMT2A (0.50) KDM4EALDH1A1HPGDLMNASCN9A
SCHEMBL8465002 0.80 KMT2A (0.50) KDM4EALDH1A1HPGDLMNASCN9A
SCHEMBL3936305 0.80 KMT2A (0.50) KDM4EALDH1A1HPGDLMNASCN9A
Hydrochloric Acid SCHEMBL7257593 0.79 KMT2A (0.49) KDM4EALDH1A1HPGDLMNASCN9A
SCHEMBL20346300 0.77 ADORA3 (0.49) ALOX5KDM4EAHRADORA3CYP1A2
SCHEMBL20543723 0.76 SCN9A (0.46) ALDH1A1SCN9ATACR1TSHRMEN1
SCHEMBL21117776 0.76 SCN9A (0.46) ALDH1A1SCN9ATACR1TSHRMEN1
SCHEMBL27552224 0.76 SCN9A (0.46) ALDH1A1SCN9ATACR1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001077095-A2 DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE NOVARTIS AG (CH) 2001-10-18 WO disclosed