Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992651 | 0.86 | LMNA (0.46) | GSK3BLMNAPTPN7DUSP3ROCK2 | |
| SCHEMBL7993214 | 0.85 | GSK3B (0.48) | GSK3BLMNAPTPN7DUSP3ROCK2 | |
| SCHEMBL7996126 | 0.84 | GSK3B (0.63) | GSK3BCDC7 | |
| SCHEMBL7990574 | 0.83 | LMNA (0.42) | GSK3BLMNAPTPN7DUSP3ROCK2 | |
| SCHEMBL7978702 | 0.82 | GSK3B (0.59) | GSK3B | |
| SCHEMBL5379886 | 0.72 | GSK3B (0.58) | GSK3BROCK2ROCK1CDC7DBF4 | |
| SCHEMBL7990818 | 0.71 | GSK3B (0.50) | GSK3BROCK2ROCK1 | |
| SCHEMBL5386895 | 0.69 | GSK3B (0.59) | GSK3BROCK2ROCK1CDC7DBF4 | |
| SCHEMBL7391761 | 0.69 | GSK3B (0.57) | GSK3BLMNAPTPN7DUSP3ROCK2 | |
| SCHEMBL7992592 | 0.68 | GSK3B (0.56) | GSK3BCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |