Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725988 | 0.89 | ENO1 (0.31) | ACHEENO1 | |
| SCHEMBL5725991 | 0.89 | ENO1 (0.31) | ACHEENO1 | |
| SCHEMBL5725518 | 0.68 | ENO1 (0.31) | ENO1 | |
| SCHEMBL14865371 | 0.64 | POLB (0.53) | POLBGAANPSR1ENO1 | |
| SCHEMBL5725264 | 0.63 | SMN1; SMN2 (0.41) | GAANPSR1 | |
| SCHEMBL5725261 | 0.63 | SMN1; SMN2 (0.41) | GAANPSR1 | |
| SCHEMBL18457392 | 0.63 | POLB (0.48) | POLBGAANPSR1 | |
| SCHEMBL19302551 | 0.59 | POLB (0.43) | POLBGAANPSR1 | |
| SCHEMBL9625099 | 0.58 | NPSR1 (0.47) | POLBGAANPSR1 | |
| SCHEMBL15248890 | 0.57 | KMT2A (0.47) | POLBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174909-B1 | FOR TREATING ANALGESIA, PSYCHOSIS, CONVULSIONS, EPILEPSY, ANXIETY, MUSCULAR AND MOVEMENT DISORDERS, SPASTIC DISORDERS OR SYMPTOMS OF HUNTINGTON'S OR PARKINSONS DISEASE | H. LUNDBECK A/S (DK) | 2001-01-16 | — | — | US | disclosed |