Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725991 | 1.00 | ENO1 (0.31) | ENO1ACHE | |
| SCHEMBL7978989 | 0.89 | POLB (0.38) | ENO1ACHE | |
| SCHEMBL5725518 | 0.70 | ENO1 (0.31) | ENO1 | |
| SCHEMBL5725261 | 0.64 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL5725264 | 0.64 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL29362852 | 0.63 | POLB (0.38) | ENO1 | |
| SCHEMBL9839151 | 0.59 | PDE4A (0.38) | ENO1 | |
| SCHEMBL28106918 | 0.55 | ENO1 (0.36) | ENO1 | |
| SCHEMBL5725154 | 0.55 | LMNA (0.34) | — | |
| SCHEMBL5725158 | 0.55 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812318-B1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |