Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899132 | 0.84 | KMT2A (0.56) | ALDH1A1CYP3A4KMT2AGAAMAOA | |
| SCHEMBL7899185 | 0.83 | MAPT (0.46) | ALDH1A1CYP3A4TAS2R38HSD17B10KMT2A | |
| SCHEMBL7638272 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2AGAAMAOBLMNA | |
| SCHEMBL7639487 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KMT2AGAALMNA | |
| SCHEMBL7645762 | 0.80 | GRIN2D (0.40) | ALDH1A1CYP3A4KMT2AGAALMNA | |
| SCHEMBL7908521 | 0.80 | MAPT (0.56) | ALDH1A1KMT2AGAAMEN1RAB9A | |
| SCHEMBL7640046 | 0.80 | MAPT (0.58) | ALDH1A1CYP3A4KMT2AGAALMNA | |
| SCHEMBL7593147 | 0.80 | MAPT (0.60) | ALDH1A1HSD17B10KMT2AGAALMNA | |
| SCHEMBL7981937 | 0.79 | MAOA (0.54) | ALDH1A1KMT2AGAAMAOAMAOB | |
| SCHEMBL7868513 | 0.79 | MEN1 (0.45) | ALDH1A1KMT2AGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |