Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980567 | 0.90 | ITGB3 (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7405357 | 0.88 | ITGAV (0.49) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7402690 | 0.87 | ITGAV (0.67) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7407106 | 0.81 | ITGB3 (0.47) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7401778 | 0.80 | ITGAV (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7985993 | 0.80 | ITGB3 (0.52) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982182 | 0.78 | ITGB3 (0.48) | ITGAVITGB3ITGA2B | |
| SCHEMBL7969330 | 0.78 | ITGB3 (0.52) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7986014 | 0.78 | ITGB3 (0.67) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7402705 | 0.78 | ITGB3 (0.48) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |