Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176105 | 0.83 | MEN1 (0.44) | RXFP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7993247 | 0.82 | KDM4E (0.43) | RXFP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8445777 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL7993333 | 0.80 | NR1H4 (0.45) | RXFP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7993464 | 0.78 | KMT2A (0.42) | KDM4EMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7991365 | 0.78 | BRPF1 (0.43) | KDM4EMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7990102 | 0.76 | NR1H4 (0.46) | RXFP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8184224 | 0.76 | MEN1 (0.44) | RXFP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7799939 | 0.73 | MEN1 (0.43) | RXFP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8182722 | 0.72 | KDR (0.43) | MEN1KMT2ASMN1; SMN2LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277861-B1 | FOR TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS, MUSCULAR DISORDERS, DRUG ADDICTION WITHDRAWAL, PAIN | SMITHKLINE BEECHAM, P.L.C. (GB) | 2001-08-21 | — | — | US | claimed |
| US-6277861-B1 | FOR TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS, MUSCULAR DISORDERS, DRUG ADDICTION WITHDRAWAL, PAIN | SMITHKLINE BEECHAM, P.L.C. (GB) | 2001-08-21 | — | — | US | disclosed |