Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798382 | 0.86 | MKNK1 (0.38) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL798359 | 0.76 | KCNA5 (0.47) | — | |
| SCHEMBL15231432 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL2576181 | 0.73 | NPC1 (0.38) | KDM4EALDH1A1MAPTNPSR1CYP1A2 | |
| SCHEMBL3390642 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL15880924 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL287699 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL18143574 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL2883986 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1MAPTL3MBTL1CYP3A4TSHR | |
| SCHEMBL9405123 | 0.68 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |