Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 13/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797912 | 0.76 | KDM4E (0.46) | — | |
| SCHEMBL798382 | 0.74 | MKNK1 (0.38) | — | |
| SCHEMBL6763911 | 0.74 | KCNA5 (0.61) | KCNA5CNR1CNR2CYP2C9 | |
| SCHEMBL27021657 | 0.73 | KCNA5 (0.52) | KCNA5CNR1CNR2P2RX7 | |
| SCHEMBL17513651 | 0.70 | KDM4E (0.59) | KCNA5CNR1CNR2 | |
| SCHEMBL4253583 | 0.69 | CNR1 (0.60) | CNR1CNR2CYP2C9 | |
| SCHEMBL30131489 | 0.69 | P2RX7 (0.58) | CNR1CNR2P2RX7 | |
| Hydrochloric Acid SCHEMBL17513110 | 0.69 | KDM4E (0.58) | KCNA5CNR1CNR2 | |
| SCHEMBL4254640 | 0.69 | CNR1 (0.58) | CNR1CNR2P2RX7 | |
| SCHEMBL14284345 | 0.69 | CNR1 (0.58) | CNR1CNR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |