SCHEMBL7979164

SCHEMBL7979164

N#CSc1ccc(N)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
MAPT P10636 6/20 0.56
POLB P06746 1/20 0.56
CYP3A4 P08684 6/20 0.45
TSHR P16473 5/20 0.45
MAPK1 P28482 1/20 0.43
CA2 P00918 2/20 0.40
CA5A P35218 2/20 0.40
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.37
ESR2 Q92731 1/20 0.37
THRB P10828 1/20 0.37
CASP1 P29466 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10801420 0.81 ALDH1A1 (0.61) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL21883260 0.81 ALDH1A1 (0.43) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL10414212 0.77 ALDH1A1 (0.46) ALDH1A1MAPTPOLBCYP3A4CA2
SCHEMBL11226980 0.76 TSHR (0.54) ALDH1A1POLBCYP3A4TSHRMAPK1
SCHEMBL272102 0.76 TSHR (0.54) ALDH1A1MAPTCYP3A4TSHRMAPK1
SCHEMBL10414211 0.76 ALDH1A1 (0.56) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL2705285 0.76 TSHR (0.45) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL693345 0.76 ALDH1A1 (0.56) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL2657481 0.76 MAPT (0.56) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL12812545 0.76 TRPV4 (0.52) ALDH1A1MAPTPOLBCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431238-A Aluminum ion detection reagent and preparation method and application thereof 河南省氟基新材料科技有限公司 2025-02-14 CN claimed
CN-119431238-A Aluminum ion detection reagent and preparation method and application thereof 河南省氟基新材料科技有限公司 2025-02-14 CN disclosed
WO-2001087850-A1 PYRIDAZINE DERIVATIVE ELEVATING PDHACTIVITY ASTRAZENECA AB (SE) 2001-11-22 WO disclosed
US-4913728-A HERBICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-03 US disclosed
US-4331817-A SULFIDING IN THE PRESENCE OF HALOGENS MINNESOTA MINING AND MANUFACTURING CO. (US) 1982-05-25 US disclosed