Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | USP4 | Q13107 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247952 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL10801420 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL10415659 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL29019053 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CA2CA5ACA12CA1 | |
| SCHEMBL5981668 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTCA2CA5ACA12 | |
| SCHEMBL2657481 | 0.76 | MAPT (0.56) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL7979164 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL10414211 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL10414946 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBCA2CA5A | |
| SCHEMBL6930947 | 0.76 | CA2 (0.40) | ALDH1A1MAPTPOLBCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999032450-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| CN-1050663-A | Produce the insecticide of benzoyl urea derivative and/or the method for ovicide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-04-17 | — | — | CN | disclosed |
| US-4913728-A | HERBICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0154508-B1 | THIOPHENYLUREAS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4843100-A | Benzoylureas, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| US-4632938-A | INSECTICIDES, OVICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| EP-0154507-A2 | Benzoylureas, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-09-11 | — | — | EP | disclosed |
| EP-0154508-A2 | Thiophenylureas, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-09-11 | — | — | EP | disclosed |
| US-4331817-A | SULFIDING IN THE PRESENCE OF HALOGENS | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1982-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | ALDH1A1 406/4885MAPT 2366/4885POLB 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.