Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436265 | 0.82 | S1PR1 (0.41) | F2F10ALOX15S1PR1LMNA | |
| SCHEMBL5225410 | 0.81 | CA12 (0.47) | F2F10ALOX15S1PR1TLR8 | |
| SCHEMBL7979172 | 0.79 | GAA (0.51) | F2F10LMNATP53ALDH1A1 | |
| SCHEMBL433953 | 0.78 | STS (0.43) | F2F10ALOX15S1PR1LMNA | |
| SCHEMBL12370192 | 0.76 | TLR8 (0.44) | F2F10ALOX15TLR8TAS1R3 | |
| SCHEMBL12117962 | 0.76 | MAPT (0.46) | F2F10ALOX15LMNATP53 | |
| SCHEMBL3244824 | 0.76 | TBXAS1 (0.51) | F2F10ALOX15TP53 | |
| SCHEMBL284155 | 0.75 | TLR8 (0.50) | F2F10ALOX15TLR8MEN1 | |
| SCHEMBL18067895 | 0.75 | S1PR1 (0.44) | F2F10S1PR1TLR8HPGD | |
| SCHEMBL2330441 | 0.75 | ALOX15 (0.58) | F2F10ALOX15LMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816103-B2 | Process for the preparation of dronedarone | SANOFI (FR) | 2014-08-26 | — | — | US | disclosed |
| EP-2595978-A1 | NOVEL PROCESS FOR THE PREPARATION OF DRONEDARONE | SANOFI (FR) | 2013-05-29 | — | — | EP | disclosed |
| US-20130131358-A1 | Novel Process for the Preparation of Dronedarone | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
| WO-2012010913-A1 | NOVEL PROCESS FOR THE PREPARATION OF DRONEDARONE | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131358-A1 | Novel Process for the Preparation of Dronedarone | CYP2F1, CYP3A4, CYP2D6 | F2 1063/4885F10 512/4885ALOX15 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.