Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850993 | 1.00 | L3MBTL1 (0.62) | L3MBTL1SIGMAR1HRH3KDM4EKMT2A | |
| SCHEMBL11205656 | 0.91 | ACHE (0.66) | SIGMAR1HRH3 | |
| SCHEMBL12929 | 0.91 | ACHE (0.66) | SIGMAR1HRH3 | |
| SCHEMBL12725 | 0.91 | ACHE (0.66) | SIGMAR1HRH3 | |
| SCHEMBL491602 | 0.90 | HRH3 (0.68) | HRH3KDM4E | |
| SCHEMBL19851112 | 0.82 | CHRNB4 (0.58) | KDM4EKMT2A | |
| SCHEMBL19850973 | 0.82 | CHRNB4 (0.58) | KDM4EKMT2A | |
| SCHEMBL10523377 | 0.82 | KDM4E (0.61) | SIGMAR1KDM4EKMT2ALTA4H | |
| SCHEMBL7289138 | 0.82 | KDM4E (0.57) | SIGMAR1KDM4EKMT2ALTA4H | |
| SCHEMBL10523381 | 0.82 | ALDH1A1 (0.68) | SIGMAR1KDM4EKMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092226-A1 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHOD OF USE THEREOF | SEPRACOR, INC. (US) | 2001-12-06 | — | — | WO | disclosed |