Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.73 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.73 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239759 | 0.84 | MAPT (1.00) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL7976297 | 0.79 | CDK5 (0.55) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL7979758 | 0.79 | KDM4E (0.48) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL7979445 | 0.79 | KDM4E (0.52) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL7982365 | 0.79 | KDM4E (0.70) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL3001277 | 0.79 | MAPT (0.52) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL6454307 | 0.79 | MAPT (0.57) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL3426469 | 0.78 | MAPT (0.56) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL3426466 | 0.78 | MAPT (0.56) | MAPTLMNATDP1HTTNCOA1 | |
| SCHEMBL3427648 | 0.76 | TUBB4A (0.68) | MAPTLMNATDP1HTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | claimed |