Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976297 | 0.83 | CDK5 (0.55) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7979445 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7979758 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3001277 | 0.83 | MAPT (0.52) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6241086 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7977857 | 0.82 | ALDH1A1 (0.72) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3427648 | 0.80 | TUBB4A (0.68) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3000687 | 0.80 | GSK3B (0.50) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7979446 | 0.79 | MAPT (0.73) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL15472018 | 0.77 | KDM4E (0.84) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | disclosed |