Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | EDNRB | P24530 | 9/20 | 0.34 |
| ▸ | EDNRA | P25101 | 9/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990192 | 0.81 | PIK3CA (0.36) | PIK3CAEDNRBEDNRAPIK3CBMAPT | |
| SCHEMBL6586303 | 0.73 | HTT (0.43) | PIK3CAEDNRBEDNRAALDH1A1MAPT | |
| SCHEMBL4068802 | 0.69 | DHPS (0.50) | EDNRBEDNRA | |
| SCHEMBL7841637 | 0.67 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL5633057 | 0.65 | MAPT (0.49) | PIK3CAEDNRBEDNRAPIK3CBALDH1A1 | |
| SCHEMBL5653603 | 0.65 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL5631503 | 0.63 | MAPT (0.49) | PIK3CAPIK3CBALDH1A1MAPTMTOR | |
| SCHEMBL5764886 | 0.63 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL6586305 | 0.61 | DHPS (0.55) | PIK3CAALDH1A1MAPTMTORLMNA | |
| SCHEMBL4068803 | 0.61 | DHPS (0.61) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |