Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 11/20 | 0.36 |
| ▸ | EDNRA | P25101 | 11/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979453 | 0.81 | PIK3CA (0.35) | PIK3CAMTOREDNRBEDNRALMNA | |
| SCHEMBL6586303 | 0.77 | HTT (0.43) | PIK3CAAKT1MTOREDNRBEDNRA | |
| SCHEMBL4068802 | 0.73 | DHPS (0.50) | EDNRBEDNRA | |
| SCHEMBL7841637 | 0.70 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL5633057 | 0.69 | MAPT (0.49) | PIK3CAAKT1MTOREDNRBEDNRA | |
| SCHEMBL5653603 | 0.68 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL5631503 | 0.67 | MAPT (0.49) | PIK3CAAKT1MTORLMNAHSD17B10 | |
| SCHEMBL5764886 | 0.66 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL4065446 | 0.65 | PIK3CA (0.51) | PIK3CALMNAHSD17B10POLBHTT | |
| SCHEMBL6586305 | 0.64 | DHPS (0.55) | PIK3CAAKT1MTORLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |