Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332474 | 0.86 | TAAR1 (0.61) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL268552 | 0.85 | RAB9A (0.69) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL346302 | 0.85 | FFAR1 (0.65) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL3257076 | 0.83 | HDAC1 (0.57) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL13545161 | 0.83 | MTNR1A (0.61) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL63100 | 0.83 | HDAC1 (0.61) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL660540 | 0.83 | TAAR1 (0.62) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL4684338 | 0.83 | CTBP2 (0.60) | TAAR1MTNR1AMTNR1BMMP13 | |
| Hydrochloric Acid SCHEMBL29194802 | 0.82 | TAAR1 (0.60) | HDAC1HDAC6TAAR1MTNR1AMTNR1B | |
| SCHEMBL18089044 | 0.81 | HDAC1 (0.62) | HDAC1HDAC6MTNR1AMTNR1BCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |