Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 17/20 | 0.56 |
| ▸ | EDNRB | P24530 | 3/20 | 0.52 |
| ▸ | EDNRA | P25101 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979438 | 0.90 | DHPS (0.56) | DHPSEDNRBEDNRA | |
| SCHEMBL7979535 | 0.89 | EDNRB (0.50) | DHPSEDNRBEDNRA | |
| SCHEMBL7993871 | 0.81 | EDNRB (0.56) | DHPSEDNRBEDNRA | |
| SCHEMBL5632783 | 0.81 | DHPS (0.58) | DHPS | |
| SCHEMBL7979436 | 0.80 | EDNRB (0.43) | DHPSEDNRBEDNRA | |
| SCHEMBL5036559 | 0.75 | DHPS (0.65) | DHPS | |
| SCHEMBL4061454 | 0.74 | DHPS (0.83) | DHPS | |
| SCHEMBL5035291 | 0.74 | DHPS (0.51) | DHPS | |
| SCHEMBL7993866 | 0.73 | EDNRB (0.55) | DHPSEDNRBEDNRA | |
| SCHEMBL30410967 | 0.73 | DHPS (1.00) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |