Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533640 | 0.98 | POLB (0.44) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL5281391 | 0.94 | POLB (0.48) | CES2CES1ALDH1A1TP53POLB | |
| SCHEMBL6567299 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6567311 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6569140 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6567779 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6568005 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6566239 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6568014 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 | |
| SCHEMBL6567797 | 0.91 | ALDH1A1 (0.50) | CES2CES1NAAAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277926-B1 | PROCESSING RUBBER BY MIXING WITH A BIS-(4-AMINOPHENYL)-CARBONYL-(1,4-PHENYLENE)-POLYSUFIDE TO INCREASE THE MOONEY VISCOSITY I.E. STIFFNESS; IMPROVED POLYMER/FILLER INTERACTION; RECEPTIVITY | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-08-21 | — | — | US | disclosed |